These models allow prediction of gene expression or alternative splicing on a GWAS study. The predicted levels can be associated to a complex trait such as a disease’s susceptibility. PrediXcan implementation uses these models and individual-level data. MetaXcan repository contains an implementation based on GWAS summary statistics (i.e. doesn’t need individual-level data). Also, a multi-tissue association is implemented there both for individual-level and summary statistics-level data.