These models allow prediction of gene expression or alternative splicing on a GWAS study. The predicted levels can be associated to a complex trait such as a disease’s susceptibility. PrediXcan implementation uses these models and individual-level data. MetaXcan repository contains an implementation based on GWAS summary statistics (i.e. doesn’t need individual-level data). Also, a multi-tissue association is implemented there both for individual-level and summary statistics-level data.


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For attribution, please cite this work as

PredictDB Team (2021). What do i do with these models?. PredictDB. /post/2021/07/21/what-do-i-do-with-these-models/

BibTeX citation

  title = "What do i do with these models?",
  author = "PredictDB Team",
  year = "2021",
  journal = "PredictDB",
  note = "/post/2021/07/21/what-do-i-do-with-these-models/"